Enhanced drug specific CD8+ T cell response at the presence of HHV-6 in DRESS patient: a case report
نویسندگان
چکیده
Background Drug rash with eosinophilia and systemic symptoms (DRESS) syndrome is a potentially life-threatening multiorgan systemic reaction that includes skin rash, fever, lymphadenopathy, internal organ involvement, and leukocytosis with eosinophilia. Evidence for reactivation of human herpes virus (HHV) 6 has been seen in some DRESS patients. We present a case of allopurinolinduced DRESS syndrome and describe the immune reactions through the identification of proliferation of CD8-positive T lymphocytes against HHV-6 peptides pool (HHV6-U90) by flow cytometry.
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